MK-677 (Ibutamoren Mesylate)

Axon Biolabs offers pure MK-677 chemical standard reagents ($\text{GHSR-1a}$) for laboratory facilities conducting non-peptide receptor signaling studies. Unlike peptide-based secretagogues, MK-677 represents a non-peptide spiroindoline compound. Furthermore, synthetic chemists engineered this molecule to selectively bind the growth hormone secretagogue receptor ($\text{GHSR}$). As a result, the chemical structure exhibits high selectivity during targeted receptor activation trials.

Researchers widely utilize this non-peptide MK-677 chemical standard reference material in structural chemistry and cellular assay models. Specifically, study teams compare non-peptide ligand kinetics against synthetic peptide agonists like our Ipamorelin pentapeptide standard. Additionally, its robust chemical stability makes it an excellent benchtop standard for chromatographic calibration. Consequently, laboratory analysts achieve high accuracy across repeated testing cycles.

Chemical Identification

• Chemical Name: Ibutamoren Mesylate / MK-677

• CAS Registry Number: 159752-10-3

• Molecular Formula: C27H36N4O5S·CH4O3S (C28H40N4O8S2)

• Molecular Weight: 624.77 g/mol

• Purity Grade: ≥98.0% (HPLC Peak Area)

• Form: Lyophilized white to off-white crystalline solid

Handling & Solubilization

Store unopened vials in a cool, dry location at -20°C for long-term stability. Furthermore, MK-677 exhibits favorable solubility in dimethyl sulfoxide (DMSO), ethanol, and aqueous buffers. However, researchers must handle solubilized stock solutions carefully to prevent light degradation. Therefore, technicians should store prepared stock solutions in tightly capped glass containers protected from ambient light sources.

Quality Documentation

Our quality control team validates every batch distributed by Axon Biolabs via nuclear magnetic resonance (NMR) spectroscopy and high-resolution LC-MS testing. Specifically, reagent standards align directly with purity specifications set on the Sigma-Aldrich Chemical Index. Therefore, researchers can easily review batch certificates stored in our public COA Library.

Legal Use Disclaimer

We manufacture this product strictly as a laboratory research chemical and analytical standard. Consequently, regulatory bodies strictly prohibit human consumption, food addition, or medical use under any circumstances.